ABOUT VIVITRA 150MG INJECTION

Vivitra 150 mg  (Trastuzumab) is a high biosimilar restorative result of reference biologic. It is an adapted monoclonal against HER2 (Human epidermal development factor receptor 2) counter acting agent. It includes 1328-amino acids; glycoprotein. 

Breast Cancer Drugs for Vivitra (Trastuzumab) is shown in which condition? 

Metastatic Breast Cancer (MBC): Vivitra  (Trastuzumab) is shown for the treatment of patients with HER2 over expressing metastatic bosom malignancy. Triumvirate (Trastuzumab) is additionally shown in blend with aromatase inhibitor for the treatment of patients with HER2 over expressing and hormone receptor-positive metastatic bosom disease. 

Early Breast Cancer (EBC): Vivitra (Trastuzumab) is shown for the treatment of patients with HER2 overexpressing early bosom malignancy following surgery, chemotherapy (neo adjuvant or adjuvant) and radiotherapy (if relevant). VivitraTM (Trastuzumab) is likewise demonstrated for adjuvant treatment of patients with HER2 overexpressing hub positive or hub negative bosom malignancy i) as a component of treatment regimen involving doxorubicin, cyclophosphamide, and either paclitaxel or docetaxel ii) with docetaxel and carboplatin. 

Metastatic Gastric Cancer (MGC): Vivitra (Trastuzumab) is shown for the treatment of patients with HER2 overexpressing metastatic gastric or gastroesophageal intersection adenocarcinoma in mix with capecitabine or 5-fluorouracil and cisplatin who have not gotten earlier hostile to malignancy treatment for their metastatic illness. 

Breast Cancer Drugs for Vivitra (Trastuzumab) work

The HER2 quality encodes the receptor tyrosine kinase HER2 and is regularly finished communicated in bosom malignancy and gastric cancer.2,3 Increased number of HER2 adds to tumor movement. 

Bosom diseases can have up to 25–50 duplicates of the HER2 quality and up to 40–100 crease increment in HER2 protein bringing about 2 million receptors communicated at the tumor cell surface. 

Expanded HER2 flagging assumes a part in expanded expansion and survival of the essential tumor and inaccessible sores endless supply of full change cause metastases. 

Around 1 out of 5 of gastric malignancies has excessively of a development advancing protein called HER2/neu (or only HER2) on the surface of the disease cells. Tumors with expanded levels of HER2 are called HER2positive-HER2 +ve.3 

Roughly 1 out of 5 patients with bosom disease has HER2-positive bosom cancer.

ABOUT VIVITRA INJECTION

Vivitra 440mg  (Trastuzumab) is a high biosimilar restorative result of reference biologic. It is an adapted monoclonal against HER2 (Human epidermal development factor receptor 2) counter acting agent. It includes 1328-amino acids; glycoprotein. 

Breast Cancer Drugs for Vivitra (Trastuzumab) is shown in which condition? 

Metastatic Breast Cancer (MBC): Vivitra  (Trastuzumab) is shown for the treatment of patients with HER2 overexpressing metastatic bosom malignancy. VivitraTM (Trastuzumab) is additionally shown in blend with aromatase inhibitor for the treatment of patients with HER2 overexpressing and hormone receptor-positive metastatic bosom disease. 

Early Breast Cancer (EBC): Vivitra (Trastuzumab) is shown for the treatment of patients with HER2 overexpressing early bosom malignancy following surgery, chemotherapy (neo adjuvant or adjuvant) and radiotherapy (if relevant). VivitraTM (Trastuzumab) is likewise demonstrated for adjuvant treatment of patients with HER2 overexpressing hub positive or hub negative bosom malignancy i) as a component of treatment regimen involving doxorubicin, cyclophosphamide, and either paclitaxel or docetaxel ii) with docetaxel and carboplatin. 

Metastatic Gastric Cancer (MGC): Vivitra (Trastuzumab) is shown for the treatment of patients with HER2 overexpressing metastatic gastric or gastroesophageal intersection adenocarcinoma in mix with capecitabine or 5-fluorouracil and cisplatin who have not gotten earlier hostile to malignancy treatment for their metastatic illness. 

Breast Cancer Drugs for Vivitra (Trastuzumab) work

The HER2 quality encodes the receptor tyrosine kinase HER2 and is regularly finished communicated in bosom malignancy and gastric cancer.2,3 Increased number of HER2 adds to tumor movement. 

Bosom diseases can have up to 25–50 duplicates of the HER2 quality and up to 40–100 crease increment in HER2 protein bringing about 2 million receptors communicated at the tumor cell surface. 

Expanded HER2 flagging assumes a part in expanded expansion and survival of the essential tumor and inaccessible sores endless supply of full change cause metastases. 

Around 1 out of 5 of gastric malignancies has excessively of a development advancing protein called HER2/neu (or only HER2) on the surface of the disease cells. Tumors with expanded levels of HER2 are called HER2positive-HER2 +ve.3 

Roughly 1 out of 5 patients with bosom disease has HER2-positive bosom cancer.

WHAT IS VOLANTIS TABLETS?

Volantis 5 mg tablet manufactured by Dr. Reddy’s, is a generic version of the drug Everolimus Tablets. It comes in a pack of 10 tablets. Volantis Tablets(Everolimus) is a prescription oncology medicine that can be purchased by a patient only against a valid prescription of a healthcare professional. 

USES OF VOLANTIS TABLETS:

Everolimus Is used For treatment of advanced renal cell cancer, after sunitinib and sorafenib treatment failure. Advanced pancreatic neuroendocrine tumors, treatment of advanced hormone receptor positive, HER2-negative breast cancer in post menopausal women, after letrozole or anastrozole treatment failure. 

Treatment of adult patients with certain types of neuroendocrine tumors (NET) of gastrointestinal (GI) or lung origin with unresectable, locally advanced or metastatic disease.

POSSIBLE SIDE EFFECTS:

EVEROLIMUS can cause a blood clot in the blood vessels of your transplanted organ, especially within 30 days after transplant. Tell your doctor right away if you have: shortness of breath, fever with nausea or vomiting, blood in your urine, dark colored urine, little or no urinating, jaundice (yellowing of your skin or eyes), or pain in your stomach, groin, lower back, or side.

COMMON SIDE EFFECTS MAY INCLUDE:

Some side effects are temporary and disappear with time, whereas other can be more severe results in major complications. Volantis 5 MG Tablet results in some minor side effects which include appetite loss, headache, problems with sleep, diarrhea and a tingling sensation in the hands and the feet. A few major side effects include kidney problems, irregular heartbeat, dizziness and severe pain in the stomach. There is also a rare chance that a patient may develop a brain infection, which can result in severe complications.

DRUGS PRECAUTIONS:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Volantis 5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Volantis 5 mg Tablet suppresses the activity of body’s immune system and prevents rejection of the transplanted organ.

DRUGS INTERACTIONS:
Do not start everolimus and consult your doctor if you have liver problems, diabetes, high blood cholesterol, had a recent surgery or have unhealed wound after surgery, have infection, previously had hepatitis, are pregnant or breast-feeding or have intolerance to some sugars.

Seek medical advice if you have increased thirst or increased frequency of urination, if you get any infection, suffer from shortness of breath, cough or fever, need to receive any vaccination after taking everolimus.

Everolimus may affect male or female fertility; consult your doctor if you are planning to have a child.

Do not drive or operate machinery while taking everolimus as it may cause fatigue.

ABOUT VONADAY

Lamivudine belongs to a class of medication called nucleoside reverse transcriptase inhibitors. It decreases the amount of virus (HIV and hepatitis) in the blood. It also increases the number of infection fighting cells in the body (CD4 cells. Tenofovir is an antiviral drug belonging to class nucleoside reverse transcriptase inhibitors (NRTIs). Efavirenz belongs to a class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It inhibits the replication of HIV, thereby reducing the amount of the virus in the blood.

MEDICINE USES :

Lamivudine indicated as part of antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infected. Tenofovir is used in combination with other antiviral drugs in the treatment of human immunodeficiency virus (HIV) infections. Efavirenz is used in combination with other medications for the treatment of human immunodeficiency virus (HIV) infection.

LAMIVUDINE/TENOFOVIR/EFAVIRENZ COMMON SIDE EFFECTS :

dizziness, drowsiness, tired feeling; nausea, diarrhea; headache, depressed mood, trouble concentrating; sleep problems (insomnia), strange dreams; rash; or changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

    unusual thoughts or behavior, anger, severe depression, thoughts of hurting yourself or others, hallucinations; a seizure (convulsions);
    kidney problems–increased thirst and urination, muscle pain or weakness; liver problems–nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
    severe skin reaction–fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
    signs of a new infection–fever, night sweats, swollen glands, mouth sores, cold sores, sores on your genital or anal area, diarrhea, stomach pain, weight loss;
    chest pain (especially when you breathe), dry cough, wheezing, feeling short of breath; rapid heart rate, feeling anxious or irritable, weakness or prickly feeling, problems with balance or eye movement;
    trouble speaking or swallowing, severe lower back pain, loss of bladder or bowel control; or swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence, loss of interest in sex.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

 VONADAY LAMIVUDINE/TENOFOVIR/EFAVIRENZ TABLETS PRECAUTIONS :

Before using this drug, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.

    Avoid pregnancy
    Discontinue use if rapid increase in aminotransferase levels, progressive hepatomegaly, or metabolic or lactic acidosis of unknown origin
    Do not take tenofovir with other drugs that can potentially damage kidneys
    Do physical examination of fat redistribution
    Have diabetes and renal impairment
    Monitor blood levels of lipids and sugar in elderly

STORAGE REQUIREMENTS :

Store at 25°C (77°F); excursions permitted between 15°C to 30°C (59°F to 86°F). Dispense only in original container; do not use if seal on bottle is broken or missing.

DRUG INTERACTIONS :

Vonaday Tablet may interact with the following drugs and products:

    Acyclovir
    Atazanavir
    Cidofovir
    Didanosine
    Ganciclovir
    Lopinavir

This document does not contain all possible interactions. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.