WHAT IS TENVIR-EM?

Emtricitabine and Tenofovir are antiviral drugs that work by preventing HIV (human immunodeficiency virus) cells from multiplying in the body. Emtricitabine belongs to a class of medication called antiretroviral medicines. Tenofovir is an antiviral drug belonging to class nucleoside reverse transcriptase inhibitors (NRTIs). Its structure closely resembles the natural structure of viral DNA, that helps it to incorporate itself into the viral DNA.

MEDICINE USES :

Emtricitabine and Tenofovir is a combination medicine used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). This medicine is not a cure for HIV or AIDS, but it can be used to treat HIV in adults and children who are at least 12 years old and weigh at least 17 kilograms (37 pounds).

COMMON SIDE EFFECTS :

headache, dizziness, feeling depressed or tired; Sleep problems (insomnia), strange dreams; stomach pain; weight loss; rash; or changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

Call your doctor at once if you have:

• sudden or unusual bone pain;
• kidney problems–little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath; or
• liver problems–nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
• signs of a new infection–fever, night sweats, swollen glands, mouth sores, diarrhea, stomach pain, weight loss;

WHAT IS TENVIR L?

Lamivudine belongs to a class of medication called nucleoside reverse transcriptase inhibitors. It decreases the amount of virus (HIV and hepatitis) in the blood. It also increases the number of infection-fighting cells in the body (CD4 cells. Tenofovir is an antiviral drug belonging to class nucleoside reverse transcriptase inhibitors (NRTIs). Its structure closely resembles the natural structure of viral DNA, that helps it to incorporate itself into the viral DNA.

MEDICINE USES :

Lamivudine indicated as part of antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infected adults and children and also used in the treatment of Hepatitis B virus infection. Tenofovir is used in combination with other antiviral drugs in the treatment of human immunodeficiency virus (HIV) infections. It may also be used in very limited cases of long-term infections of liver caused by hepatitis B virus.

LAMIVUDINE/TENOFOVIR COMMON SIDE EFFECTS :

diarrhea; cold symptoms such as stuffy nose, sneezing, sore throat; or abnormal liver function tests.

Some people develop lactic acidosis while taking Lamivudine/Tenofovir. Early symptoms may get worse over time and this condition can be fatal. Get emergency medical help if you have even mild symptoms such as:

• muscle pain or weakness; numb or cold feeling in your arms and legs; trouble breathing; feeling dizzy, light-headed, tired, or very weak;
• stomach pain, nausea with vomiting; or fast or uneven heart rate.

TETANUS (lock jaw) VACCINE :
Brand Name    : Tetanus (Lock Jaw)
Content            : Tetanus Toxoid 5 Lf, Adsorbed on Aluminium Phosphate (AlPO4) 1.5 mg & Thiomersal   0.01 % as preservative
Strength           : 0.5 mg
Form                  : Injection

 TIGI 50 mg INJECTION 

Tigi is an antibiotic that fights bacteria in the body. It works by killing sensitive bacteria.

MEDICINE USES :

Tigecycline is used to treat many different bacterial infections of the skin or the digestive system, as well as pneumonia.

NATCO TIGECYCLINE 50 mg SIDE EFFECTS :

    nausea, vomiting, stomach pain;
    diarrhea;
    headache; or
    abnormal liver function tests
    severe stomach pain, diarrhea that is watery or bloody;
    increased pressure inside the brain – severe headache, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes;
    pancreas problems – severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate; or
    liver problems – nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

SAFETY INFORMATION (Precautions) for TIGI TIGECYCLINE INJECTION :

    Before using Tigecycline, tell your doctor or pharmacist if you are allergic to it; or to tetracyclines (such as doxycycline, minocycline, tetracycline); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
    Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe liver disease.
    This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
    This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors.
    Before having surgery, tell your doctor or dentist that you are using this medication.
    This medication should not be used in children younger than 8 years of age because it may cause permanent tooth discoloration and other problems. Tooth discoloration may also occur in older children and young adults. Consult your doctor for more information.
    This medication is not recommended for use during pregnancy because of possible harm to an unborn baby. Consult your doctor for more details.
    It is not known whether this drug passes into breast milk. Because of possible harm to a nursing infant, consult your doctor before breast-feeding.

This is not a complete list. Ask your health care provider for more information.

STORAGE REQUIREMENTS :

Tigecycline should be stored at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F).

DRUG INTERACTIONS :

Some products that may interact with this drug include: “blood thinners” (e.g., warfarin), live bacterial vaccines, retinoid medications taken by mouth (such as acitretin, isotretinoin).

This document does not contain all possible interactions. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

What is Trifluridine/Tipiracil?

Trifluridine/Tipiracil is a combination medication used in the treatment of specific cancers, including metastatic colorectal cancer (cancer that has spread) and certain types of gastric or gastroesophageal junction adenocarcinoma after previous treatments have not been successful. It combines two active ingredients: trifluridine, a nucleoside metabolic inhibitor, and tipiracil, a thymidine phosphorylase inhibitor, which together work to inhibit cancer cell growth.

How does Trifluridine/Tipiracil work?

The medication works through a two-pronged approach:

• Trifluridine is incorporated into the DNA of cancer cells, preventing them from replicating and leading to their death.
• Tipiracil increases the availability of trifluridine by inhibiting its degradation, ensuring that enough trifluridine can be incorporated into the DNA of cancer cells to be effective.

Who should take Trifluridine/Tipiracil?

Tipanat Trifluridine/Tipiracil Tablets is prescribed for adults with metastatic colorectal cancer who have previously been treated with fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy, an anti-VEGF biological therapy, and if RAS wild-type, an anti-EGFR therapy. It is also used for the treatment of adult patients with metastatic gastric or gastroesophageal junction adenocarcinoma previously treated with at least two prior lines of chemotherapy.

How is Trifluridine/Tipiracil administered?

Natco Trifluridine/Tipiracil Tablets are administered orally in tablet form. The dosage and treatment schedule depends on the patient’s condition, body surface area, and how well they tolerate the treatment. Typically, the treatment involves taking the tablets on specific days followed by a rest period.

What are the side effects of Trifluridine/Tipiracil?

Like all medications, Trifluridine/Tipiracil can cause side effects. Common side effects include:

• Neutropenia (low levels of white blood cells)
• Anaemia (low red blood cell count)
• Thrombocytopenia (low platelet count)
• Fatigue
• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Fever

Patients should report any side effects to their healthcare provider, as some may require medical attention.

Can everyone with metastatic colorectal cancer or gastric cancer use Trifluridine/Tipiracil?

Not everyone with metastatic colorectal cancer or gastric cancer will be eligible for Indian Trifluridine Tipiracil Tablets. The suitability of this medication depends on several factors, including previous treatments, the specific characteristics of the cancer, and the patient’s overall health. Decisions regarding treatment with Trifluridine/Tipiracil should be made in consultation with a healthcare provider specializing in cancer treatment.

How effective is Trifluridine/Tipiracil?

The effectiveness of Generic Trifluridine/Tipiracil Tablets varies from person to person. Clinical trials have shown that it can extend survival in patients with metastatic colorectal cancer and gastric cancer who have exhausted other treatment options. However, it is not considered a cure for these cancers. The goal of treatment with Trifluridine/Tipiracil is to slow the progression of the disease and improve the quality of life.

Where can I get more information?

For more information about Trifluridine/Tipiracil, speak with your healthcare provider. They can provide personalized information based on your medical history and condition. Additionally, reputable cancer organizations and the official website LetsMeds Pharmacy for Lonsurf offer detailed information about the medication, its uses, and its side effects.

Conclusion

Trifluridine/Tipiracil represents an important treatment option for patients with certain advanced cancers. While it offers hope for extending life and improving the quality of life, patients and their families must discuss all potential benefits and risks with their healthcare team. Understanding more about how Trifluridine/Tipiracil works, who it’s for, and its potential side effects can help patients make informed decisions about their treatment options.