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( reviews)
Nerlynx 40mg Neratinib Tablets
$50.00Neratinib Tablet
Neratinib is an anti-cancer targeted therapy drug. Neratinib is classified as a “Tyrosine Kinase Inhibitor.” Neratinib is used as adjuvant therapy in people with early-stage breast cancer in which HER2 is overexpressed.
Nerlynx 40mg Tablet
Nerlynx 40mg Tablet is the trade name of Generic Neratinib used to treat Breast Cancer.
Nerlynx Uses
Nerlynx Tablet is used to treat adults who have early-stage breast cancer, which:
- is HER2-positive and
- has previously been treated with the medicine trastuzumab.
How to take Nerlynx Tablet
Neratinib tablets come in one strength, 40 mg, taken by mouth.
Take prescribed dose once daily by mouth with food.
Take Nerlynx exactly as prescribed by the specialist.
Take at approximately the same time each day.
Swallow Nerlynx Tablets whole, do not crush, dissolve or open capsules.
Do not change your dose or stop Nerlynx unless your specialist tells you to.
If you miss a dose of neratinib, resume therapy with the next scheduled daily dose; do not replace the missed dose.
Nerlynx Side Effects
Most people will not experience all of the side effects listed for neratinib nerlynx tablet.
Neratinib side effects will improve after therapy is complete.
The following Side Effects are Common
Diarrhea, Nausea, Vomiting, and Stomach Pain.
The following Side Effects are Less Common
Fatigue, Skin Rash, Pain and Sores inside the mouth, Poor Appetite and Muscle Spasms.
How Nerlynx Works
Neratinib Nerlynx is a tyrosine kinase inhibitor (TKI) a small molecule that work is blocking transduction signal through the epidermal growth factor receptor (EGFR) HER2. These receptors are accountable for helping cancer cells develop and multiply.
DRUGS PRECAUTIONS:
Before taking Nerlynx, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Do not receive any kind of immunization or vaccination without your doctor’s approval while taking cabozantinib.
If you are taking digoxin, talk with your doctor. You may need to have your blood work checked more closely while you are taking this drug.
Avoid taking H2-receptor antagonists (famotidine, cimetidine, ranitidine), proton pump inhibitors, If necessary, take antacids 3 hours before taking neratinib tablet.It is not known whether this drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.
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( reviews)
Nevimune – Nevirapine 200mg Tablets
$50.00ABOUT NEVIMUNE
Nevimune belongs to a class of anti-HIV medicines called non-nucleoside reverse transcriptase inhibitors (NNRTIs). Reverse transcriptase is an enzyme that HIV needs in order to multiply. It stops reverse transcriptase from working, and thus helps control HIV-1 infection.
MEDICINE USES :
Nevirapine is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body. It is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). It will not prevent or cure HIV or AIDS.
NEVIRAPINE SIDE EFFECTS :
mild nausea, vomiting, diarrhea, or stomach pain; muscle pain; headache, tired feeling; or changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).
Stop using Nevirapine and call your doctor at once if you have:
fever, swollen gums, painful mouth sores, pain when swallowing, skin sores, cold or flu symptoms, cough, trouble breathing;
any other signs of new infection; or the first sign of any skin rash, no matter how mild.This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
NEVIMUNE NEVIRAPINE TABLETS PRECAUTIONS :
·
Before taking NEVIMUNE, tell your doctor or pharmacist if you are allergic to it; or if you
have any other allergies. This product may contain inactive ingredients, which
can cause allergic reactions or other problems. Talk to your pharmacist for
more details.·
Before using this
medication, tell your doctor or pharmacist your medical history, especially of:
diabetes, heart problems (coronary disease, heart attack), lipid problems (high
cholesterol or triglycerides/fats), hemophilia, and liver problems.·
Before having
surgery, tell your doctor or dentist about all the products you use (including
prescription drugs, nonprescription drugs, and herbal products).·
Children may be
more sensitive to the side effects of this drug, especially diarrhea or rash.
Tell your doctor if you are pregnant before using this
medication.·
It is unknown if
this medication passes into breast milk. Because breast milk can transmit HIV,
do not breast-feed.This is not a complete list. Ask your health care provider for more information.
STORAGE REQUIREMENTS :
Store at 20° to 25°C (68° to 77°F). Store in a safe place out of the reach of children.
DRUG INTERACTIONS :
Many drugs can interact with Nevirapine, or make it less effective. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with Nevirapine, especially:
maraviroc;
fentanyl, methadone;
a blood thinner (warfarin, Coumadin);
an antibiotic such as clarithromycin or rifabutin;
antifungal medicine such as fluconazole or voriconazole;
ergot medicine such as ergotamine, dihydroergotamine, ergonovine, or methylergonovine;
heart or blood pressure medications such as amiodarone, diltiazem, disopyramide, felodipine, nifedipine, verapamil, and others;
medication to prevent organ transplant rejection;
other HIV medicines such as darunavir, fosamprenavir, nelfinavir, indinavir, ritonavir, or saquinavir; or
seizure medication such as carbamazepine, clonazepam, or ethosuximide. -
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Nexavar 200mg Sorafenib Tablets
$50.00NEXAVAR SORAFENIB TABLETS
NEXAVAR SORAFENIB TABLETS conform to the class of drugs called multikinase inhibitors. It slows down the rate of growth of cancer cells by blocking the action of an abnormal protein that signals cancer cells to multiply. It reduces the blood supply to the cancer cells and stops their growth and proliferation.
NEXAVAR USES
This medication is used to treat kidney or liver cancer. It may also be used to treat a certain type of thyroid cancer (differentiated thyroid carcinoma). NEXAVAR SORAFENIB TABLETS stops or slows the growth of cancer cells (tumors). It also works by slowing the growth of new blood vessels within the tumor.
NEXAVAR COMMON SIDE-EFFECTS
Acne, dry skin, nausea, diarrhea, patchy hair loss/thinning, loss of appetite, dry mouth, hoarseness, or tiredness may occur. If these effects persist or worsen, notify your doctor or pharmacist promptly.
This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high. Your doctor may control your blood pressure with medication.
Skin problems – (such as rash, blisters, redness, swelling, pain)
Tell your doctor right away if you have signs of an underactive thyroid (such as weight gain, cold intolerance, slow heartbeat, constipation, or unusual tiredness) or signs of an overactive thyroid (such as mental/mood changes, heat intolerance, fast/pounding/irregular heartbeat, unusual weight loss).
Signs of liver problems – (such as stomach/abdominal pain, persistent nausea/vomiting, yellowing eyes/skin, dark urine).
Get medical help right away if you have any very serious side effects, including chest/jaw/left arm pain, severe abdominal/stomach pain, bloody vomit, coughing up blood, bloody stools, difficulty speaking, loss of balance, sudden vision changes, seizures, severe dizziness, fainting.
Signs of an infection – such as fever, chills or a persistent sore throat.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
WARNING & PRECAUTIONS
Before taking NEXAVAR SORAFENIB TABLETS, inform your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
Do not have immunizations/vaccinations without the consent of your doctor, and avoid contact with people who have recently received vaccine.
If you need to have a surgical or dental procedure, tell your doctor or dentist that you are using NEXAVAR SORAFENIB TABLETS.
Tell your doctor if you are breast-feeding or plan to breast-feed. You should not breast-feed while taking this cancer treatment.
Avoid contact sports or other activities where bruising or injury could occur.
Wash your hands well to prevent the spread of infections.
You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress.
STORAGE
Store at 25°C (77°F); excursions are permitted between 15°C and 30°C (59°F and 86°F). Protect from moisture.
NEXAVAR SORAFENIB TABLETS INTERACTIONS
Some products that may interact with this drug include: other anti-cancer drugs (such as docetaxel, doxorubicin, irinotecan), “blood thinners” (anticoagulants such as warfarin, heparins), neomycin taken by mouth.
Other medications can affect the removal of NEXAVAR SORAFENIB TABLETS from your body, which may affect how NEXAVAR SORAFENIB TABLETS works. Examples include dexamethasone, rifamycins (such as rifampin/rifabutin), St. John’s wort, drugs used to treat seizures (such as carbamazepine, phenytoin, phenobarbital), among others.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.
DISPOSAL
If your doctor tells you to stop taking this medicine or the expiry date has passed, ask your pharmacist what to do with any medicine you have left over.
NOTE
We strongly encourage you to talk with your health care professional about your specific medical condition and treatments. The information contained in this website is meant to be helpful and educational but is not a substitute for medical advice.
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( reviews)
Nicorette – Chewing Gum
$50.00Brand Name : Nicorette Chewing GumContents : Nicotine PolacrilexForm : Chewing GumStrength : 2mg / 4mg -
( reviews)
Nicotex (Nicotine Polacrilex) Chewing Gum
$50.00Brand Name : NicotexContents : Nicotine PolacrilexForm : Chewing GumManufactured By : CiplaStrength available : 2mg / 4mg -
( reviews)
Nindanib Capsules | Indian Nintedanib
$50.00Nindanib Nintedanib Capsules :
Nintedanib (BIBF 1120) is a medication used to treat chronic lung disease and non-small cell lung cancer (NSCLC). Recently Glenmark Pharma launched a generic Nintedanib called Nindanib Capsules (strength 100mg & 150mg). It is sold under the brand name Ofev and Vargatef.
Generic Nintedanib Capsules Uses :
The medication is used to treat –
Idiopathic Pulmonary Fibrosis (a type of chronic scarring lung disease).
Lung Cancer – Second-line treatment for adult patients with metastatic non-small cell lung cancer (NSCLC).
Nintedanib Capsules Generic Brands :
(Available in the strength of 100mg & 150mg)
Cyendiv Capsules By Boehringer Ingelheim
Nindanib by Glenmark Pharmaceuticals
Nintenib by BDR Pharmaceuticals
Nintena by Sun Pharmaceuticals
Nintib by Cipla Ltd.
Buy Original Generic Nintedanib Capsules at Wholesale Price :
LetsMeds a Trusted Medicines Exporter of original Generic Nintedanib Capsules to the countries Singapore, China, USA, UAE, Philippines, HongKong, Vietnam, Taiwan, Malaysia, etc. We are working towards improving the lives of people by supplying original generic life expectancy medicines at affordable prices.If you wish to order Indian Nintedanib Capsules at wholesale price, you just need to fill the “ASK Price” form and contact us at Mail: info@LetsMeds.Com. -
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Nintedanib Capsules Generic Brands India
$50.00Nintedanib Capsules :
Nintedanib (BIBF 1120) is a medication used to treat chronic lung disease and non-small cell lung cancer (NSCLC). It is sold under the brand name Ofev and Vargatef and in India sold under the name Cyendiv. Many Generic Nintedanib Capsules (strength 100mg & 150mg), available such as Nindanib by Glenmark, Nintib by Cipla, etc. LetsMeds a Trusted Medicines Exporter help you to provide these medicines at reasonable prices. Contact us at Mail: info@LetsMeds.Com, WeChat: LetsMeds.
Generic Nintedanib Capsules Uses :
The medication is used to treat –
Idiopathic Pulmonary Fibrosis (a type of chronic scarring lung disease).
Lung Cancer – Second-line treatment for adult patients with metastatic non-small cell lung cancer (NSCLC).
Nintedanib Capsules Generic Brands India :
(Available in the strength of 100mg & 150mg)
Cyendiv By Boehringer Ingelheim
Nindanib Capsules by Glenmark Pharmaceuticals
Nintenib by BDR Pharmaceuticals
Nintena by Sun Pharmaceuticals
Nintib by Cipla Ltd.
Cyendiv Capsules Side Effects
Abdominal Pain,
Constipation,
Dizziness,
Diarrhea,
Fever,
Headache,
Hair Loss,
Weightloss,
Tiredness, etc.
This is not the full list of side effects, if you see any of these side effects immediately consult with your doctor.
Buy Original Generic Nintedanib Capsules at Wholesale Price :
LetsMeds a Trusted Medicines Exporter of original Indian Nintedanib Capsules to the countries Singapore, China, USA, UAE, Philippines, Hong Kong, Vietnam, Taiwan, Malaysia, etc. We are working towards improving the lives of people by supplying original generic life expectancy medicines at affordable prices.If you wish to order Generic Nintedanib Capsules wholesale price in India, you just need to fill the “ASK Price” form and contact us at Mail: info@LetsMeds.Com. -
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( reviews)
Niraparix 尼拉帕利 Capsules
$50.00产品介绍:
尼拉帕利（Niraparib，在香港的商品名：则乐），是一种高效、选择性的每日一次口服小分子聚（ADP-核糖）PARP1/2抑制剂，用于晚期复发性卵巢癌的维持治疗，可显著延长晚期卵巢癌病人的生存期，减少卵巢癌的复发。
尼拉帕利于2017年3月在美国获得FDA批准上市，同年11月在欧洲获批，用于对含铂化疗完全或部分缓解的复发性上皮卵巢癌、输卵管癌或原发性腹膜癌患者的维持治疗。基于在美国和欧洲的获批，则乐（尼拉帕利）已于2018年10月在香港获批上市。
PARP抑制剂（PARPi）是基于卵巢癌精准治疗的药物，也是卵巢癌治疗史上的一大突破。目前，全球已有三种PARP抑制剂（尼拉帕利，奥拉帕利，芦卡帕利）获批用于卵巢癌的治疗，其中尼拉帕利是首个在美国获批不用检测BRCA的维持治疗的PARP抑制剂。
研究结果表明，在“化疗间歇期”中使用尼拉帕利维持相较于安慰剂，无论病人是否存在BRCA胚系突变都有奇效：
（1）在gBRCA突变阴性患者中，疾病进展风险降低了55%，PFS延长到2倍以上（9.3个月对比3.9个月）；
（2）而在gBRCA突变阳性患者中有更为显著的效果，疾病进展风险降低了73%，PFS延长到近4倍（21个月对比5.5个月）。这提示，BRCA突变是尼拉帕利治疗获益的有利因素，相较于奥拉帕利和芦卡帕利，这种研究更加全面。
（3）在gBRCA突变阴性但HRD阳性的患者中效果也很显著，疾病进展风险降低了70%，PFS延长3倍以上（12.9个月对比3.8个月）。
尽管三种PARP抑制剂（尼拉帕利、奥拉帕利、芦卡帕利）均获美国FDA批准用于复发性卵巢癌的维持治疗，但三种PARP抑制剂还是具有一定区别：
（1）三种PARP抑制剂的药理和药代动力学特性不同。尼拉帕利生物利用度高达73%和更长的人体半衰期（36h），在肿瘤组织中高暴露量而显示出更好的抗肿瘤活性；同时由于尼拉帕利特殊的代谢途径，服用其他药物不需要对尼拉帕利进行药物剂量调整。
（2）患者用药的便利性与依从性不同。尼拉帕利是每日服用一次，临床应用起来非常方便，患者依从性高。而奥拉帕利、芦卡帕利一般需要一天服用2~3次。并且，卵巢癌患者服用尼拉帕利不需要做BRCA基因检测，患者无论有没有BRCA基因突变，都能获得疗效。
（3）患者用药安全性不同。尼拉帕利用于一线化疗后维持治疗的PRIMA研究结果显示，体重小于77 kg的患者若初始剂量为200 mg，每天1次，则其血液学毒性明显减少，且不影响药物疗效。尼拉帕利基于体重和/或血小板计数的个体化给药方案，可降低血液学治疗突发不良事件的发生率。
在2018年，全球范围内有超过30万女性被诊断为卵巢癌。仅在中国，每年就有5万多女性被诊断，2万多人因此而去世。
卵巢癌之所以难治，一个核心原因就是早期没有症状，极难发现和筛查，所以基本一发现就是晚期，疾病已经转移，治疗起来比较困难。这点和“癌中之王”胰腺癌比较像。 以往，卵巢癌维持治疗使用的主要是化疗，效果不够理想，由于缺乏更好的药物，患者只能等待和观察。但尼拉帕利为代表的PARP抑制剂获批后，打破了30年的囧境，明显延长患者的无进展生存期，并且减少复发次数。
碧康制药生产的Niraparix是尼拉帕利在全球的首仿药，也是迄今为止唯一获得政府监管机构批准合法生产的仿制药。
碧康制药由欧洲财团参与投资，是南亚地区唯一执行欧盟技术规范，并且在孟加拉两大证券交易所主板上市的大型制药企业，产品符合欧洲药典和美国药典标准。
相比其他来源不清晰的所谓同一种仿制药，即使其主要成份含量与碧康产品相接近，但由于不具备严格规范的GMP标准生产场所和政府部门的严格监管，其产品中影响药物吸收率的溶出度和生物利用度也与碧康产品具有很大差异。
为保证用药安全，敬请谨慎选择！
适应症:
尼拉帕利是一种聚(ADP-核糖)聚合酶(PARP)抑制剂，适用于有复发性表皮卵巢癌、输卵管癌、原发性腹膜癌的成年患者（需对基于铂化疗有完全或部分缓解）的维持治疗。
用法与用量:
1. 推荐剂量是300m（3粒），口服，每天1次，有或无食物服用。
2. 继续治疗直至疾病进展或不可接受不良反应。
3. 对不良反应，考虑中断治疗，剂量减低或给药终止。
常见不良反应：
恶心（74%）、血小板减少症（61%）、疲劳乏力（57%）、贫血（50%）、便秘（40%）、呕吐（34%）、腹痛腹胀（33%）、嗜中性白血球减少症（30%）、失眠（27%）、头疼（26%）、食欲减退（25%）、鼻咽炎（23%）、皮疹（21%）、高血压（20%）、呼吸困难（20%）、腹泻（20%）、口腔炎/黏膜炎（20%）等。
特殊人群中使用：
哺乳：建议妇女治疗期间和接受最后给药后共1个月不要哺乳喂养。
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( reviews)
Nirmatrelvir & Ritonavir Tablets Nirmacom Combipack
$50.00Nirmatrelvir & Ritonavir Tablets Nirmacom Combipack: A New Oral Medicine for COVID-19
COVID-19 is a global pandemic that has affected millions of people and caused many deaths. The disease is caused by a new coronavirus that can infect the respiratory system and other organs. The symptoms of COVID-19 can range from mild to severe, and some people may develop serious complications, such as pneumonia, blood clots, organ failure, or death.
There is no specific cure for COVID-19, but there are several treatments and medications that can help reduce the severity of the infection and prevent hospitalization or death. One of the most promising treatments is Nirmacom, a new oral drug that has been approved by the World Health Organization (WHO) and the Drugs Controller General of India (DCGI) for mild to moderate COVID-19 in adults who are at higher risk of severe illness.
What are Nirmacom Tablets?
Nirmacom Tablets are a combination of two antiviral drugs: Nirmatrelvir and Ritonavir. Nirmatrelvir Tablets are a SARS-CoV-2 main protease inhibitor, which means that it blocks an enzyme that the virus needs to replicate. Ritonavir is an HIV antiretroviral drug that boosts the levels of Nirmatrelvir in the body and enhances its effectiveness.
Nirmacom is manufactured by Hetero, one of India’s leading pharmaceutical companies with a global reach. Hetero entered into a non-exclusive voluntary licensing agreement with Medicines Patent Pool (MPP) for manufacturing and selling a generic version of Pfizer’s COVID-19 oral antiviral drug Paxlovid, which contains the same active ingredients as Nirmacom.
How does Nirmacom Tablet work?
Nirmacom works by preventing the growth and multiplication of the coronavirus in the body. By inhibiting the viral protease enzyme, Nirmatrelvir stops the virus from making new copies of itself. By increasing the concentration of Nirmatrelvir & Ritonavir Tablets Online ensures that enough drug reaches the infected cells and prevents the virus from escaping or developing resistance.
By reducing the viral load, Nirmacom can help alleviate the symptoms of COVID-19 and prevent the disease from progressing to severe stages. Nirmacom can also reduce the risk of transmission to others by lowering the amount of virus in the respiratory tract.
How effective is Nirmacom Tablet?
Nirmacom has been shown to be highly effective in reducing the risk of hospitalization or death due to COVID-19. According to clinical trials conducted by Pfizer, Paxlovid reduced the risk of hospitalization or death by 89% compared to placebo in high-risk patients who started treatment within three days of symptom onset. The results were similar for patients who started treatment within five days of symptom onset.
According to Hetero, Nirmacom has also demonstrated comparable efficacy and safety to Paxlovid in clinical trials conducted in India. Nirmacom has received emergency use authorization (EUA) from the DCGI and prequalification from the WHO, which means that it meets the quality, safety, and efficacy standards for treating COVID-19.
How to use Nirmacom Tablet?
Nirmacom is available as a combi pack that contains Nirmatrelvir 150 mg (2 tablets) and Ritonavir 100 mg (1 tablet). It is prescribed by a doctor and should be taken as soon as possible after a diagnosis of COVID-19 and within five days of symptom onset. The recommended dose is two tablets of Nirmatrelvir and one tablet of Ritonavir twice a day for five consecutive days. Nirmacom can be taken with or without food.
Nirmacom should not be given to children below 12 years of age or weighing less than 40 kg. It should also not be taken by people who are allergic to Nirmatrelvir or Ritonavir or have severe liver or kidney disease. Nirmacom may interact with other medicines, so it is important to inform your doctor about all the medicines you are taking before starting Nirmacom.
What are the side effects of the Nirmacom Tablet?
Nirmacom is generally well tolerated and has mild to moderate side effects. The most common side effects are taste change, diarrhea, vomiting, high blood pressure, and muscle pain. These side effects usually go away after stopping Nirmacom.
However, some people may experience serious side effects, such as allergic reactions, liver problems, heart problems, bleeding problems, or drug resistance. If you notice any signs of these side effects, such as rash, difficulty breathing, yellowing of the skin or eyes, chest pain, irregular heartbeat, blood in urine or stool, or worsening symptoms of COVID-19, you should seek immediate medical attention.
Conclusion:
Nirmacom is a new oral drug that can help treat mild to moderate COVID-19 in high-risk adults. It is a combination of two antiviral drugs that work by blocking the virus from replicating and spreading in the body. It can reduce the risk of hospitalization or death due to COVID-19 by 89%. It is approved by the WHO and the DCGI and manufactured by Hetero in India. It should be taken as soon as possible after a diagnosis of COVID-19 and within five days of symptom onset. It has mild to moderate side effects, but some people may experience serious side effects that require medical attention.
Nirmacom is a breakthrough in the fight against COVID-19 and can help save lives and prevent severe outcomes. However, it is not a substitute for vaccination and prevention measures. The best way to protect yourself and others from COVID-19 is to get vaccinated and follow the public health guidelines, such as wearing a mask, washing your hands, avoiding crowds, and staying home if you are sick.
Medical Disclaimer:
In order to legally purchase this medicine from LetsMeds, you’ll require a prescription from your Registered Medical Practitioner.
Note:
All content found on LetsMeds, including medicine uses, dosage/administration, adverse effects, and storage details are created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice. Always consult your doctor or other qualified health professionals if you have any questions regarding your health, medicine, or medical condition.
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