NATDECITA 

Natdecita 50mg is a cancer medication that interferes with the growth and spread of cancer cells in the body. It is a type of drug called a hypomethylating agent. It works by switching off a protein called DNA methyltransferase. This switches on genes that stop the cancer cells growing and dividing.

MEDICINE USES :

Natco Decitabine is used to treat myelodysplastic syndromes (diseases of the blood and bone marrow; MDS) and certain types of anemia. It is an antineoplastic (cancer medicine).

DECITABINE COMMON SIDE EFFECTS :

headache, dizziness, drowsiness; nausea, vomiting, stomach pain, diarrhea, constipation; cough, dry mouth; joint pain; or sleep problems (insomnia).

Call your doctor at once if you have:

    fever, chills, body aches, cough, sore throat, flu symptoms;
    easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
    pale skin, feeling light-headed, rapid heart rate, trouble concentrating;
    white patches or sores inside your mouth or on your lips; or
    stabbing chest pain, wheezing, feeling short of breath, cough with yellow or green mucus;
    swelling, pain, tenderness, or redness anywhere on your body; or
    electrolyte imbalance (confusion, uneven heart rate, extreme thirst, increased urination, jerking muscle movements, leg discomfort, muscle weakness or limp feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

NATDECITA DECITABINE INJECTION PRECAUTIONS :

·        
Natdecita may
cause dizziness or blurred vision. These effects may be worse if you take it
with alcohol or certain medicines. Use this medicine with caution. Do not drive
or perform other possibly unsafe tasks until you know how you react to it.

·        
Natdecita may
lower the ability of your body to fight infection. Avoid contact with people
who have colds or infections. Tell your doctor if you notice signs of infection
like fever, sore throat, rash, or chills.

·        
Decitabine may
raise your blood sugar. High blood sugar may make you feel confused, drowsy, or
thirsty. It can also make you flush, breathe faster, or have a fruit-like
breath odor. If these symptoms occur, tell your doctor right away.

·        
Lab tests,
including complete blood and platelet counts and liver and kidney function tests
may be performed while you use it. These tests may be used to monitor your
condition or check for side effects. Be sure to keep all doctor and lab
appointments.

·        
PREGNANCY and
BREAST-FEEDING: Decitabine may cause harm to the fetus. Do not become pregnant
while you are using it and for 1 month after you stop using it. It is not known
if this medicine is found in breast milk. Do not breast-feed while using it.

This is not a complete list. Ask your health care provider for more information.

STORAGE REQUIREMENTS :

Store at 20° to 25°C (68° to 77°F); excursions permitted between 15° and 30°C (59° and 86°F)

DRUG INTERACTIONS :

Drug interactions may change how your medications work or increase your risk for serious side effects. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

NATZOLD Infusion:

MEDICINE USES:

ZOLEDRONIC ACID SIDE EFFECTS:

• fever, chills, flu symptoms, flushing (warmth, redness, or tingly feeling); severe joint, bone, or muscle pain; new or unusual pain in your thigh or groin;
• pale skin, feeling light-headed or short of breath; hypocalcemia–numbness or tingly feeling in your fingers or toes or around your mouth, twitching, muscle spasms or cramps; signs of a kidney problem–little or no urinating; painful or difficult urination; swelling, rapid weight gain; feeling tired or short of breath; or
• severe skin reaction–fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
• Serious side effects on the kidneys may be more likely in older adults.

ZOLEDRONATE INJECTIONS PRECAUTIONS:

• Do not use Natzold if you are pregnant. It could harm the unborn baby.
• Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
• Some people using medicines similar to Natzold have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms of this condition may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums.
• Avoid having any type of dental surgery while you are being treated with Natzold. It may take longer than normal for you to recover.
• Natzold can harm your kidneys. This effect is increased when you also use other medicines harmful to the kidneys, such as chemotherapy, antiviral medication, pain or arthritis medicine, injected antibiotics, or medicines to treat a bowel disorder or prevent organ transplant rejection.

ZOLEDRONIC STORAGE REQUIREMENTS :

DRUG INTERACTIONS:

WHAT IS NAVELBINE INJECTION?

Inorelbine is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug.  This medication is classified as a “plant alkaloid.” Vinorelbine is cancer medication that interferes with the growth of cancer cells and slows their spread in the body.

USES OF NAVELBINE INJECTION:

Vinorelbine is used to treat various types of cancer. It is a chemotherapy drug that works by slowing or stopping cancer cell growth.

Vinorelbine is given by injection only into a vein by a healthcare professional. It is usually given over 6-10 minutes, once a week, or as directed by your doctor. The dosage is based on your medical condition, response to therapy, and body size.

POSSIBLE SIDE EFFECTS:

A very serious allergic reaction to this drug is unlikely, but gets medical help right away if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, and breathing. 

Nausea, vomiting, fatigue, constipation, diarrhea, dizziness, muscle aches, joint pain, or irritation at the injection site may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Temporary hair loss may occur. Normal hair growth should return after treatment has ended.

To prevent constipation, eat a diet adequate in fiber and drink plenty of water. Your doctor may also prescribe a laxative (such as a stool softener) to help prevent constipation.

COMMON SIDE EFFECTS MAY INCLUDE:

People using this medication may have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk offside effects. Careful monitoring by your doctor may decrease your risk.

Tell your doctor right away if you have any serious side effects, including: numbness/tingling/pain in the hands or feet, decreased reflexes, mouth sores, easy bruising/bleeding, weakness, new or increased trouble breathing, cough, severe constipation, stomach/abdominal pain, blood in the urine, mental/mood changes.

DRUGS PRECAUTIONS:

Before using vinorelbine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: decreased bone marrow function/blood cell disorders (e.g., anemia, leukopenia and thrombocytopenia).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, numbness/tingling of the hands or feet, blockage of the stomach/intestines (e.g., obstruction, paralytic ileus), heart disease.

DRUGS INTERACTIONS:

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/non-prescription drugs and herbal products) and share it with your doctor and pharmacist. Does not start, stop, or change the dosage of any medicines without your doctor’s approval.

A product that may interact with this drug is: mitomycin.

Other medications can affect the removal of vinorelbine from your body, which may affect how vinorelbine works. Examples include azole antifungals (such as itraconazole), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John’s wort, drugs used to treat seizures (such as carbamazepine), among others.

WHAT IS NEOBEN INJECTION?

Vinorelbine is an antineoplastic. It works by targeting cancer cells and interfering with their reproduction.

USES OF NEOBEN INJECTION:

Neoben 10 Mg Injection is a potent anti-cancer medication prescribed to primarily combat non-small cell type of lung cancers. You may also be prescribed this medicine if you are suffering from certain types of ovarian cancer or breast cancer, and sometimes in case of Hodgkin’s disease. The drug works inhibiting the process of cancel cell division, thereby it stunts the spread or growth of cancer. 

POSSIBLE SIDE EFFECTS:

The medicine is not available in a form that can be taken orally. It is generally injected intravenously by a medical expert in a clinic. The Neoben 10 Mg Injection drug can be classified as a vesicant. This may lead to severe tissue damage and blistering of the skin and surrounding healthy tissues, if it is not administered properly in the veins. You must alert your doctor immediately if you start noticing reddening of the skin surface, along with pain or swelling at the site of injection. 

COMMON SIDE EFFECTS MAY INCLUDE:

The medicine is not recommended to breastfeeding mothers as the drug is known to be excreted in the human milk which eventually passes on to the infant, causing major health complications. You are advised to not conceive during the course of the treatment. You must abstain from drinking alcohol, smoking, caffeine and tobacco during the course of treatment.

Side Effects of Neoben are Nausea, Vomiting, Weakness, Fatigue, Hair loss, Low blood platelets, Increased liver enzymes, Fever, Anemia (low number of red blood cells), Bleeding, Constipation.

DRUGS PRECAUTIONS:

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Neoben 10 mg Injection blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.

DRUGS INTERACTIONS:

Inform your doctor if you have a history of heart problems, vascular problems or low production of blood cells from the bone marrow (myelosupression); liver problems or have had radiotherapy around the liver.

Do not take live or attenuated vaccines during therapy and avoid contact with people who receive them.

Use two methods of contraception while on this therapy and 3 months after it to avoid pregnancy.

Men should not father a child while on this therapy and 3 months post it. They should also seek guidance and counselling on sperm conservation before taking this therapy.

Avoid contact with skin, eyes or mucosa as vinorelbine may cause irritation. Thoroughly wash the skin area, in case of skin contact with the medicine.

Take vinorelbine preferably with a light meal to reduce nausea. Soft capsule gels of vinorelbine should not be taken with hot fluids, as the medicine may quickly dissolve.

Vinorelbine is not recommended in children below 18 years.

Neoben Injection Specifications:

Brand Name : Neoben

Composition : Vinorelbine 50 mg

Manufactured by : Neon Laboratories Ltd.

Form : Injection

Packing : Pack of 1 Vial

Country Of Origin : India

WHAT IS NEOBEN INJECTION?

Vinorelbine is an antineoplastic. It works by targeting cancer cells and interfering with their reproduction.

USES OF NEOBEN INJECTION:

Neoben 50 Mg Injection is a potent anti-cancer medication prescribed to primarily combat non-small cell type of lung cancers. You may also be prescribed this medicine if you are suffering from certain types of ovarian cancer or breast cancer, and sometimes in case of Hodgkin’s disease. The drug works inhibiting the process of cancel cell division, thereby it stunts the spread or growth of cancer. 

POSSIBLE SIDE EFFECTS:

The medicine is not available in a form that can be taken orally. It is generally injected intravenously by a medical expert in a clinic. The Neoben 50 Mg Injection drug can be classified as a vesicant. This may lead to severe tissue damage and blistering of the skin and surrounding healthy tissues, if it is not administered properly in the veins. You must alert your doctor immediately if you start noticing reddening of the skin surface, along with pain or swelling at the site of injection. 

COMMON SIDE EFFECTS MAY INCLUDE:

The medicine is not recommended to breastfeeding mothers as the drug is known to be excreted in the human milk which eventually passes on to the infant, causing major health complications. You are advised to not conceive during the course of the treatment. You must abstain from drinking alcohol, smoking, caffeine and tobacco during the course of treatment.

Side Effects of Neoben are Nausea, Vomiting, Weakness, Fatigue, Hair loss, Low blood platelets, Increased liver enzymes, Fever, Anemia (low number of red blood cells), Bleeding, Constipation.

DRUGS PRECAUTIONS:

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Neoben 50 mg Injection blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.

DRUGS INTERACTIONS:

Inform your doctor if you have a history of heart problems, vascular problems or low production of blood cells from the bone marrow (myelosupression); liver problems or have had radiotherapy around the liver.

Do not take live or attenuated vaccines during therapy and avoid contact with people who receive them.

Use two methods of contraception while on this therapy and 3 months after it to avoid pregnancy.

Men should not father a child while on this therapy and 3 months post it. They should also seek guidance and counselling on sperm conservation before taking this therapy.

Avoid contact with skin, eyes or mucosa as vinorelbine may cause irritation. Thoroughly wash the skin area, in case of skin contact with the medicine.

Take vinorelbine preferably with a light meal to reduce nausea. Soft capsule gels of vinorelbine should not be taken with hot fluids, as the medicine may quickly dissolve.

Vinorelbine is not recommended in children below 18 years.