Uses

WHAT IS NAVELBINE INJECTION?

Inorelbine is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug.  This medication is classified as a “plant alkaloid.” Vinorelbine is cancer medication that interferes with the growth of cancer cells and slows their spread in the body.

USES OF NAVELBINE INJECTION:

Vinorelbine is used to treat various types of cancer. It is a chemotherapy drug that works by slowing or stopping cancer cell growth.

Vinorelbine is given by injection only into a vein by a healthcare professional. It is usually given over 6-10 minutes, once a week, or as directed by your doctor. The dosage is based on your medical condition, response to therapy, and body size.

POSSIBLE SIDE EFFECTS:

A very serious allergic reaction to this drug is unlikely, but gets medical help right away if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, and breathing. 

Nausea, vomiting, fatigue, constipation, diarrhea, dizziness, muscle aches, joint pain, or irritation at the injection site may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Temporary hair loss may occur. Normal hair growth should return after treatment has ended.

To prevent constipation, eat a diet adequate in fiber and drink plenty of water. Your doctor may also prescribe a laxative (such as a stool softener) to help prevent constipation.

COMMON SIDE EFFECTS MAY INCLUDE:

People using this medication may have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk offside effects. Careful monitoring by your doctor may decrease your risk.

Tell your doctor right away if you have any serious side effects, including: numbness/tingling/pain in the hands or feet, decreased reflexes, mouth sores, easy bruising/bleeding, weakness, new or increased trouble breathing, cough, severe constipation, stomach/abdominal pain, blood in the urine, mental/mood changes.

DRUGS PRECAUTIONS:

Before using vinorelbine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: decreased bone marrow function/blood cell disorders (e.g., anemia, leukopenia and thrombocytopenia).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, numbness/tingling of the hands or feet, blockage of the stomach/intestines (e.g., obstruction, paralytic ileus), heart disease.

DRUGS INTERACTIONS:

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/non-prescription drugs and herbal products) and share it with your doctor and pharmacist. Does not start, stop, or change the dosage of any medicines without your doctor’s approval.

A product that may interact with this drug is: mitomycin.

Other medications can affect the removal of vinorelbine from your body, which may affect how vinorelbine works. Examples include azole antifungals (such as itraconazole), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John’s wort, drugs used to treat seizures (such as carbamazepine), among others.

ABOUT NELVIR 

Nelvir belongs to a class (group) of HIV drugs called protease inhibitors (PIs). PIs block an HIV enzyme called protease. (An enzyme is a protein that starts or increases the speed of a chemical reaction.) By blocking protease, PIs prevent HIV from multiplying and can reduce the amount of HIV in the body.

MEDICINE USES :

Nelfinavir is used for treating HIV infection in combination with other medicines. It is an HIV protease inhibitor. It works by blocking a substance that is needed for the HIV virus to multiply.

NELFINAVIR  SIDE EFFECTS :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; gas; loss of appetite; nausea; stomach pain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever, chills, or sore throat; mental or mood changes; suicidal thoughts or actions; symptoms of high blood sugar (eg, confusion; flushed face; fruit-like breath odor; increased thirst, hunger, or urination; unusual drowsiness); unusual bleeding or bruising.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

 NELVIR NELFINAVIR TABLETS PRECAUTIONS :

·        
Before taking
Nelvir, tell your doctor or pharmacist if you are allergic to it; or if you
have any other allergies. This product may contain inactive ingredients, which
can cause allergic reactions or other problems. Talk to your pharmacist for
more details.

·        
Before using this
medication, tell your doctor or pharmacist your medical history, especially of:
diabetes, heart problems (coronary disease, heart attack), lipid problems (high
cholesterol or triglycerides/fats), hemophilia, and liver problems.

·        
Before having
surgery, tell your doctor or dentist about all the products you use (including
prescription drugs, nonprescription drugs, and herbal products).

·        
Children may be
more sensitive to the side effects of this drug, especially diarrhea or rash.
 Tell your doctor if you are pregnant before using this
medication.

·        
It is unknown if
this medication passes into breast milk. Because breast milk can transmit HIV,
do not breast-feed.

This is not a complete list. Ask your health care provider for more information.

STORAGE REQUIREMENTS :

Store at room temperature of 15°C to 30°C (59°F to 86°F).

DRUG INTERACTIONS :

Many drugs can interact with Nelfinavir. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:

    any other antiviral medicines to treat HIV;
    bosentan;
    carbamazepine;
    colchicine;
    fluticasone;
    methadone;
    midazolam injection;
    omeprazole;
    quetiapine;
    salmeterol;
    warfarin (Coumadin, Jantoven);
    an antibiotic – azithromycin, rifabutin;
    cholesterol medication – atorvastatin, rosuvastatin;
    medicine to prevent organ transplant rejection – cyclosporine, sirolimus, tacrolimus;
    medicine to treat impotence or pulmonary arterial hypertension – avanafil (Stendra), sildenafil (Viagra), tadalafil (Adcirca, Cialis), or vardenafil (Levitra, Staxyn); or
    seizure medicine – phenobarbital, phenytoin.

This document does not contain all possible interactions. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

WHAT IS NEOCTIDE INJECTION?

Octreotide is a hormone drug that is
used to treat some types of cancer.  Octreotide is a man-made protein that
is similar to a hormone in the body called somatostatin. Octreotide lowers many
substances in the body such as insulin and glucagon (involved in regulating
blood sugar), growth hormone, and chemicals that affect digestion.

USES
OF NEOCTIDE INJECTION:

Octreotide  is given to
control symptoms such as diarrhea or flushing in patients with tumors such as
carcinoid, pancreatic islet cell tumors, gastrinoma, or vasoactive intestinal
peptide-secreting tumors (VIPomas). It is also used to treat acromegaly, when
the body produces too much growth hormone, and the hands, feet, face or head
grow too large.

POSSIBLE SIDE EFFECTS:

severe stomach pain or
tenderness, severe constipation; slow or uneven heartbeats;
severe pain in your upper stomach spreading to your back,
nausea and vomiting, fast heart rate;
high blood sugar–increased thirst, increased urination,
hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision,
weight loss;
low blood sugar–headache, hunger, weakness, sweating,
confusion, irritability, dizziness, fast heart rate, or feeling jittery; or
underactive thyroid–extreme tired feeling, dry skin, joint
pain or stiffness, muscle pain or weakness, hoarse voice, feeling more
sensitive to cold temperatures, weight gain.

COMMON SIDE EFFECTS MAY
INCLUDE:

diarrhea, constipation;
vomiting, upset stomach; bloating, gas; headache, dizziness; or pain when
injecting the medicine.

Diarrhoea, Abdominal pain,
Nausea, Constipation, Flatulence, Headache, Increased glucose level in blood,
Gallstones, Injection site reaction.

DRUGS INTERACTIONS: 

Neoctide 0.05 mg Injection
is a similar to somatostatin, a substance normally found in the human body
which inhibits the effects of certain hormones such as growth hormone. It also
lowers the bleeding from the food pipe by constricting (narrowing) the blood
vessels.

Your doctor or nurse will
give you this medicine. Kindly do not self administer.

DRUGS PRECAUTIONS:

Seek medical attention if you experience
disturbances in your line of vision.

Your thyroid function and liver function will
be monitored during octreotide therapy.

Do not drive or operate machines while on
octreotide treatment as it may cause blurred vision and headache.

Inform your doctor if you are taking a
medicine to control your blood pressure or if you are a patient with diabetes.

If you are a woman of child bearing age,
effective contraceptive method should be adopted during treatment with
octreotide.

Tell your doctor if you are or planning to
become pregnant or are breastfeeding.

Neratinib Tablet 

Neratinib is an anti-cancer targeted therapy drug. Neratinib is classified as a “Tyrosine Kinase Inhibitor.” Neratinib is used as adjuvant therapy in people with early-stage breast cancer in which HER2 is overexpressed. 

Nerlynx 40mg Tablet

Nerlynx 40mg Tablet is the trade name of Generic Neratinib used to treat Breast Cancer. 

Nerlynx Uses

Nerlynx Tablet is used to treat adults who have early-stage breast cancer, which:

• is HER2-positive and
• has previously been treated with the medicine trastuzumab.
• 
  
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How to take Nerlynx Tablet

Neratinib tablets come in one strength, 40 mg, taken by mouth. 

Take prescribed dose once daily by mouth with food.

Take Nerlynx exactly as prescribed by the specialist. 

Take at approximately the same time each day.

Swallow Nerlynx Tablets whole, do not crush, dissolve or open capsules.

Do not change your dose or stop Nerlynx unless your specialist tells you to.

If you miss a dose of neratinib, resume therapy with the next scheduled daily dose; do not replace the missed dose.

Nerlynx Side Effects 

Most people will not experience all of the side effects listed for neratinib nerlynx tablet.

Neratinib side effects will improve after therapy is complete.

The following Side Effects are Common 

Diarrhea, Nausea, Vomiting, and Stomach Pain.  

The following Side Effects are Less Common 

Fatigue, Skin Rash, Pain and Sores inside the mouth, Poor Appetite and Muscle Spasms. 



How Nerlynx Works

Neratinib Nerlynx is a tyrosine kinase inhibitor (TKI) a small molecule that work is blocking transduction signal through the epidermal growth factor receptor (EGFR) HER2. These receptors are accountable for helping cancer cells develop and multiply.

DRUGS PRECAUTIONS: