Glivec 100mg  Imatinib Tablets Novartis India LTD Wholesale Price

Imatinib is a Small molecule kinase inhibitor used to treat certain kinds of tumor. It is presently advertised by Novartis as Gleevec (USA) or Glivec (Europe/Australia) as its mesylate salt, Imatinib, sold under the brand names Gleevec among others, Imatinib is a chemotherapy pharmaceutical used to treat cancerLike CML and ALL are sorts of leukemia in which a strange chromosome creates a chemical that prompts uncontrolled development of white platelets. Glivec slaughters the unusual cells while allowing typical cells to sit unbothered. Glivec Tablets is likewise used to treat grown-ups for: myelodysplastic/myeloproliferative maladies (MDS/MPD). For More 伊马替尼 进行更多翻译 Trade Query : , WeChat:LetsMeds , Worldwide Supplier Of Imatinib Mesylate Tablets Like China, Hongkong, Singapore, UAE, USA, UK  and other countries.

Novartis Glivec Imatinib 100 Mg Tablets 

Glivec  Tablets

Novartis Glivec 100mg tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells. 

Glivec Imatinib 100 mg USES

Imatinib (伊马替尼 )is utilized for treating certain sorts of leukemia, certain bone marrow maladies, a specific kind of skin disease, and certain intestinal tumors (eg, gastrointestinal stromal tumors [GIST]). It might likewise be utilized to keep tumor from developing in patients after surgical evacuation of GIST. 

 COMMON SIDE EFFECTS :

Irritated stomach, queasiness/spewing, looseness of the bowels, migraine, muscle/joint agony, muscle spasms, unsteadiness, obscured vision, or sluggishness may happen. On the off chance that any of these impacts last or deteriorate, tell your specialist or drug specialist quickly. 

Tell your specialist immediately on the off chance that you have any genuine reactions, including: simple wounding/dying, abnormal tiredness, sudden/unexplained weight pick up, swelling hands/lower legs/feet/mid-region, swelling around the eyes, shortness of breath, quick pulse, dark/wicked stools, upchuck that resembles espresso beans, side effects of liver illness, (for example, sickness/heaving that doesn’t stop, loss of hunger, stomach/stomach torment, yellowing eyes/skin, dim pee). 

This is not a total rundown of conceivable reactions. On the off chance that you see some other impacts not recorded above, contact your specialist or drug specialist. 

 Imatinib 100 mg Precautions :

Before taking imatinib 100mg , tell your specialist or drug specialist in the event that you are hypersensitive to it; or on the off chance that you have some other sensitivities. This item may contain idle fixings, which can cause unfavorably susceptible responses or different issues. Converse with your drug specialist for more points of interest. 

Before utilizing this pharmaceutical, tell your specialist or drug specialist your therapeutic history, particularly of: draining issues, heart issues, (for example, heart disappointment), kidney illness, liver infection, expulsion of thyroid organ. 

This medication may influence you to bleary eyed or sluggish or cause obscured vision. Try not to drive, utilize hardware, or do any movement that requires sharpness or clear vision until the point that you are certain you can perform such exercises securely. Utmost mixed refreshments. 

Imatinib can make you more prone to get diseases or may intensify any ebb and flow contaminations. Maintain a strategic distance from contact with individuals who have diseases that may spread to others, (for example, chickenpox, measles, influenza). Counsel your specialist on the off chance that you have been presented to a contamination or for more points of interest. 

Try not to have inoculations/immunizations without the assent of your specialist. Keep away from contact with individuals who have as of late gotten live antibodies, (for example, influenza immunization breathed in through the nose). 

Before having surgery, inform your specialist or dental specialist concerning every one of the items you utilize (counting physician recommended drugs, nonprescription medications, and natural items). 

More seasoned grown-ups might be more touchy to the symptoms of this medication, particularly swelling (edema). 

Tell your specialist in the event that you are pregnant or plan to end up plainly pregnant. You ought not end up noticeably pregnant while you are taking imatinib. Imatinib may hurt an unborn child. Get some information about dependable types of conception prevention while taking this pharmaceutical. On the off chance that you wind up plainly pregnant while taking imatinib, converse with your specialist immediately about the dangers and advantages of this pharmaceutical. 

This drug goes into bosom drain. On account of conceivable hazard to the baby, bosom encouraging while at the same time utilizing this medication is not suggested. Counsel your specialist before bosom bolstering. 

Appropriate STORAGE OF Glivec  :

Store Glivec at 20º to 25ºC (68º to 77ºF); trips allowed to 15 to 30ºC (59 to 86ºF) 

IMATINIB PROPER INTERACTIONS :

This Medicine can communicate with different medicines, vitamins, or herbs you might be taking. A cooperation is the point at which a substance changes the way a medication works. This can be hurtful or keep the medication from functioning admirably. 

To help maintain a strategic distance from associations, your specialist ought to deal with the greater part of your meds painstakingly. Make certain to educate your specialist concerning all solutions, vitamins, or herbs you’re taking. To discover how this medication may connect with something unique you’re taking, converse with your specialist or drug specialist.

Here are Harvoni (Ledipasvir/sofosbuvir) costs in :

– the US ($94,500)

– Canada ($80,000)

– India ($900)

– the UK (£39,000)

– Germany (48,000€)

– Egypt ($1200)

This medicine is a mix of ledipasvir and sofosbuvir and is utilized to treat incessant (durable) hepatitis C, a viral contamination of the liver. It might once in a while be utilized with another antiviral medicine (ribavirin). These medications work by lessening the measure of hepatitis C infection in your body, which enables your insusceptible framework to battle the contamination and may enable your liver to recuperate. Endless hepatitis C contamination can cause genuine liver issues, for example, scarring (cirrhosis), or liver tumor. 

It is not known whether this treatment can keep you from passing the infection to others. Try not to share needles, and practice “more secure sex” (counting the utilization of latex condoms) to bring down the danger of passing the infection to others. 

Step by step instructions to utilize Harvoni 

Read the Patient Information Leaflet if accessible from your drug specialist before you begin taking ledipasvir/sofosbuvir and each time you get a refill. On the off chance that you have any inquiries, ask your specialist or drug specialist. 

Take this pharmaceutical by mouth with or without nourishment as coordinated by your specialist, ordinarily once every day. 

This pharmaceutical works best when the measure of medication in your body is kept at a steady level. In this way, take this medication at uniformly divided interims. To enable you to recollect, take it in the meantime every day. 

Tell your specialist on the off chance that you upchuck inside 5 hours in the wake of taking this prescription. You may need to take another dosage. 

Keep on taking ledipasvir/sofosbuvir for the full timeframe endorsed, regardless of the possibility that manifestations vanish a little while later. Ceasing the medicine too soon may bring about an arrival of the disease. 

Acid neutralizers bring down the retention of ledipasvir. On the off chance that you are taking an acid neutralizer, take it no less than 4 hours earlier or 4 hours after this prescription. 

Other corrosive bringing down meds for acid reflux, indigestion, or ulcers, (for example, medicine or over-the-counter meds including famotidine, omeprazole) may keep ledipasvir from working. Ask your specialist or drug specialist how to utilize these medicines securely.

Doses & Administration

Each tablet contains 90 mg ledipasvir and 400 mg sofosbuvir. Tablets include the following inactive ingredients: colloidal silicon dioxide, copovidone, croscarmellose sodium, lactose monohydrate, magnesium stearate, and microcrystalline cellulose. These tablets are film-coated with a coating material containing the following inactive ingredients: FD&C yellow #6/sunset yellow FCF aluminum lake, polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide.

It is indicated with or without ribavirin for the treatment of patients with chronic hepatitis C virus (HCV) genotype 1, 4, 5, or 6 infection.

Harvoni Side Effects:

If Harvoni is administered with ribavirin, refer to the prescribing information for ribavirin for a description of ribavirin-associated adverse reactions. The safety assessment was based on pooled data from three randomized, open-label Phase 3 clinical trials (ION-3, ION-1 and ION-2) of subjects with genotype 1 HCV with compensated liver disease (with and without cirrhosis) including 215, 539, and 326 subjects who received once daily by mouth for 8, 12 and 24 weeks, respectively.

The proportion of subjects who permanently discontinued treatment due to adverse events was 0%, less than 1%, and 1% for subjects receiving these tablets for 8, 12, and 24 weeks, respectively.

The most common adverse reactions (at least 10%) were fatigue and headache in subjects treated with 8, 12, or 24 weeks of Harvoni.

Potential For Drug Interaction

As Harvoni contains ledipasvir and sofosbuvir, any interactions that have been identified with these agents individually may occur with tablets.

After oral administration of tablets, sofosbuvir is rapidly absorbed and subject to extensive first-pass hepatic extraction. In clinical pharmacology studies, both sofosbuvir and the inactive metabolite GS-331007 were monitored for purposes of pharmacokinetic analyses. Ledipasvir is an inhibitor of the drug transporters P-gp and breast cancer resistance protein (BCRP) and may increase intestinal absorption of coadministered substrates for these transporters.

Ledipasvir and sofosbuvir are substrates of drug transporters P-gp and BCRP while GS-331007 is not. P-gp inducers (e.g., rifampin or St. John’s wort) may decrease ledipasvir and sofosbuvir plasma concentrations, leading to reduced therapeutic effect of Harvoni, and the use with P-gp inducers is not recommended with Harvoni.

TAF，替诺福韦二代。　新药彻底治愈乙肝不可能，但能实现临床治愈。 　　TAF能实现临床治愈，是目前乙肝治疗界公认的最高水平。　什么是临床治愈?又为什么治愈不可能?摊开来讲好比将军带兵攻打敌国，大败敌军生擒国王，将其下监，严加看管，此后四海之内再无敌军，这就是临床治愈。但这国王装疯卖傻以求活命，并仍有一定的可能在守卫疏忽之时越狱，东山再起，这就是无法完全治愈。　　TAF作为替诺福韦第二代，几乎没有肾毒性，取代替诺福韦TDF是早晚的问题。

具体表现在：　　

1.更好的骨骼安全性　　2.更好的肾脏安全性　　3.耐药性最低　　4.十分之一剂量，可达到国内一线治疗药物TDF的同等药效　　我适合服用TAF吗? 　　

TAF并非适合每一个乙肝患者，

它更加适合以下患者：　　

1.首次服用抗病毒药物的乙肝患者　　2.在服用其他抗病毒药物的患者，更换药物时需询问医生　　3.服用其他药物时，在3年内产生耐药性的，强烈推荐　　4.为预防乙肝妈妈将病毒传给宝宝，哺乳期妇女建议使用　　5.还患有糖尿病或肾损伤、骨质疏松严重的患者. 

 ABOUT HEPCDAC

HEPCDAC (Daclatasvir) is an antiviral medicine that prevents hepatitis C virus (HCV) from multiplying in your body.

MEDICINAL USES :

Daclatasvir is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.

HEPCDAC COMMON SIDE EFFECTS :

Tiredness, headache, nausea, or diarrhea may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

SAFETY INFORMATION (Precautions) :

    Before taking daclatasvir, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
    Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease other than hepatitis C.
    Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
    During pregnancy, daclatasvir should be used only when clearly needed. Discuss the risks and benefits with your doctor. Daclatasvir, in combination with ribavirin, must not be used during pregnancy by either the pregnant woman or her male partner. The combination may harm an unborn baby. Two reliable forms of birth control (such as condoms, birth control pills) must be used whenever at least one sexual partner is using these medicines together, and for six months after stopping treatment. If you or your partner becomes pregnant, or if you think you or your partner may be pregnant, tell your doctor right away.
    It is unknown if daclatasvir passes into breast milk. Consult your doctor before breast-feeding. Breast-feeding is not recommended if daclatasvir is used in combination with ribavirin.

PROPER STORAGE OF HEPCDAC :

Store at 25°C (77°F); excursions permitted between 15°C and 30°C (59°F and 86°F).

HEPCDAC INTERACTIONS :

Amiodarone may interact with sofosbuvir. Tell your doctor and pharmacist if you are taking amiodarone.

Other medications can affect the removal of daclatasvir from your body, which may affect how daclatasvir works. Examples include rifampin, St. John’s wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.

This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.