Synthivan – Atazanavir/Ritonavir Tablets

ABOUT SYNTHIVAN

Atazanavir belongs to a group of medication called azapeptide HIV-1 protease inhibitor. It inhibits some viral polypeptides in the HIV-1 infected cells of the body and inhibits and prevents maturation of virus in the cells. This medication does not cure HIV infections; it decreases the risks of developing acquired immunodeficiency syndrome (AIDS) and other HIV-related illnesses due to compromised immunity. Ritonavir belongs to a class of medication called protease inhibitors. It prevents HIV from multiplying inside the body.

MEDICINE USES :

Atazanavir is used in combination with other anti-retroviral medicines for the treatment of human immunodeficiency virus (HIV-1) infection. Ritonavir is used along with other medication for treating human immunodeficiency virus (HIV 1) infection. It does not completely cure HIV or acquired immunodeficiency syndrome (AIDS).

ATAZANAVIR/RITONAVIR COMMON SIDE EFFECTS :

nausea, vomiting, stomach pain; muscle pain, mild itching or rash; headache, dizziness, depressed mood, sleep problems (insomnia);
numbness or burning pain in your hands or feet; or changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

Atazanavir/Ritonavir may increase your risk of certain infections or autoimmune disorders by changing the way your immune system works. Symptoms may occur weeks or months after you start treatment with these. Tell your doctor if you have:

    signs of a new infection–fever, night sweats, swollen glands, diarrhea, stomach pain, weight loss; chest pain (especially when you breathe), dry cough, wheezing, feeling short of breath;
    cold sores, sores on your genital or anal area; rapid heart rate, feeling anxious or irritable, weakness or prickly feeling, problems with balance or eye movement;
    trouble speaking or swallowing, severe lower back pain, loss of bladder or bowel control; or swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence, loss of interest in sex.
    headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
    severe pain in your side or lower back, painful urination, blood in your urine;
    jaundice (yellowing of the skin or eyes);
    high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision); or
    severe skin reaction — fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

 SYNTHIVAN ATAZANAVIR/RITONAVIR TABLETS PRECAUTIONS:

Before using this drug, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.

    Avoid spreading of HIV virus to others
    Children
    Consult a doctor if you have haemophilia or pancreatitis
    Kidney problems
    Liver problems or liver disease including hepatitis B or C
    Monitor glucose, lipid and uric acid regularly

STORAGE REQUIREMENTS :

Store at 25°C (77°F); excursions are permitted between 15°C and 30°C (59°F and 86°F).

DRUG INTERACTIONS :

Synthivan Tablet may interact with the following drugs and products:

    Amiodarone
    Amlodipine
    Astemizole
    Atorvastatin
    Avanafil
    Axitinib

This document does not contain all possible interactions. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.