What is Abrocitinib Tablet is used for?

Abrocitinib Tablet is a treatment for moderate to severe atopic eczema (also known as atopic dermatitis) in adults and children aged 12 years and older. It’s a type of drug known as a Janus kinase (JAK) inhibitor. Abrocitinib is taken orally, as a tablet. It calms the immune system and reduces eczema inflammation (red or darker areas of active eczema) and itch.

How does Abrocitinib Tablet work?

Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin condition in which the body’s immune system attacks healthy skin cells.

The active substance in abrocitinib, acts on enzymes known as Janus kinase-1 (JAK1). These enzymes play an important role in the process of inflammation that is seen in atopic dermatitis. By blocking JAK1’s action, abrocitinib helps reduce the inflammation and other symptoms of atopic dermatitis

Are there any known adverse reactions or side effects of Abrocitinib?

Common adverse reactions

The most common side effects (≥10% of patients) listed in the prescribing information include:

• Feeling sick in the stomach (nausea)
• Cold sores (herpes simplex)
• Vomiting
• Upper abdominal pain
• Headache
• Dizziness
• Acne
• Increase in an enzyme called creatine phosphokinase, shown by blood test