Trioday Tablets (Efavirenz + Lamivudine + Tenofovir )

ABOUT TRIODAY 

Lamivudine belongs to a class of medication called nucleoside reverse transcriptase inhibitors. It decreases the amount of virus (HIV and hepatitis) in the blood. It also increases the number of infection fighting cells in the body (CD4 cells. Tenofovir is an antiviral drug belonging to class nucleoside reverse transcriptase inhibitors (NRTIs). Efavirenz belongs to a class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It inhibits the replication of HIV, thereby reducing the amount of the virus in the blood.

MEDICINE USES :

Lamivudine indicated as part of antiretroviral combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infected. Tenofovir is used in combination with other antiviral drugs in the treatment of human immunodeficiency virus (HIV) infections. Efavirenz is used in combination with other medications for the treatment of human immunodeficiency virus (HIV) infection.

LAMIVUDINE/TENOFOVIR/EFAVIRENZ COMMON SIDE EFFECTS :

dizziness, drowsiness, tired feeling; nausea, diarrhea; headache, depressed mood, trouble concentrating; sleep problems (insomnia), strange dreams; rash; or changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

    unusual thoughts or behavior, anger, severe depression, thoughts of hurting yourself or others, hallucinations; a seizure (convulsions);
    kidney problems–increased thirst and urination, muscle pain or weakness; liver problems–nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
    severe skin reaction–fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
    signs of a new infection–fever, night sweats, swollen glands, mouth sores, cold sores, sores on your genital or anal area, diarrhea, stomach pain, weight loss;
    chest pain (especially when you breathe), dry cough, wheezing, feeling short of breath; rapid heart rate, feeling anxious or irritable, weakness or prickly feeling, problems with balance or eye movement;
    trouble speaking or swallowing, severe lower back pain, loss of bladder or bowel control; or swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence, loss of interest in sex.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

TRIODAY LAMIVUDINE/TENOFOVIR/EFAVIRENZ TABLETS PRECAUTIONS :

Before using this drug, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.

    Avoid pregnancy
    Discontinue use if rapid increase in aminotransferase levels, progressive hepatomegaly, or metabolic or lactic acidosis of unknown origin
    Do not take tenofovir with other drugs that can potentially damage kidneys
    Do physical examination of fat redistribution
    Have diabetes and renal impairment
    Monitor blood levels of lipids and sugar in elderly

STORAGE REQUIREMENTS :

Store at 25°C (77°F); excursions permitted between 15°C to 30°C (59°F to 86°F). Dispense only in original container; do not use if seal on bottle is broken or missing.

DRUG INTERACTIONS :

Trioday Tablet may interact with the following drugs and products:

    Acyclovir
    Atazanavir
    Cidofovir
    Didanosine
    Ganciclovir
    Lopinavir

This document does not contain all possible interactions. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.