Aggrenox 25 mg Tablets

WHAT IS
AGGRENOX TABLETS? 

Aggrenox contains a combination of Aspirin and Dipyridamole.
Aspirin belongs to a group of drugs called salicylates (sa-LIS-il-ates). It
works by reducing substances in the body that cause pain, fever, and
inflammation. Dipyridamole keeps platelets in your blood from sticking together
to form clots.

Aggrenox 25mg/200mg Capsule MR is a
combination of two antiplatelet medicines: Aspirin and Dipyridamole which
prevent stroke following an initial first stroke (transient ischemic attack).
It works by preventing platelets from sticking together which decreases the
formation of harmful blood clots.

USES OF
AGGRENOX TABLETS:

This medication is used to reduce
the risk of stroke in
patients who have had “mini-strokes” (transient ischemic attacks) or
a previous stroke due to a blood
clot and are at high risk for another stroke. It contains two medications: a very low dose of aspirin (25 milligrams per tablet) and dipyridamole in a slow-release form.

Low-dose aspirin and dipyridamole are
anti platelet drugs that work to keep blood flowing to the brain by stopping platelets from clumping together. This
helps prevent the platelets from forming blood clots, which can lodge in the brain and cause a certain type of stroke (ischemic stroke).

Aggrenox is used to reduce the risk of
stroke in people who have had blood clots or a “mini-stroke” (also
called a transient ischemic attack or TIA).

POSSIBLE
SIDE EFFECTS:

Some side effects of aspirin /
dipyridamole may occur that usually do not need medical attention. These side
effects may go away during treatment as your body adjusts to the medicine.
Also, your health care professional may be able to tell you about ways to
prevent or reduce some of these side effects. Check with your health care
professional if any of the following side effects continue or are bothersome or
if you have any questions about them:

new or worsening chest pain;
a light-headed feeling, like you might pass out;
hearing problems, ringing in your ears;
liver problems – nausea, upper stomach pain, itching,
tiredness, loss of appetite, dark urine, clay-colored stools, jaundice
(yellowing of the skin or eyes);
signs of stomach bleeding – stomach pain, severe heartburn,
bloody or tarry stools, coughing up blood or vomit that looks like coffee
grounds; or
signs of bleeding in the brain – confusion, memory problems,
severe headache, fainting.

COMMON
SIDE EFFECTS MAY INCLUDE:

Headache, nausea, vomiting, diarrhea, abdominal
pain, heartburn, and dizziness may occur. Talk with your doctor
if you have a severe headache when you first start taking this medication.
Your doctor may change your dose for the first week to lessen headache. If
any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and light-headedness,
get up slowly when rising from a sitting or lying position.

Remember that your doctor has
prescribed this medication because he or she has judged that the benefit to you
is greater than the risk of side effects. Many people using this medication do
not have serious side effects.

Side Effects of Aggrenox are
Nausea, Diarrhoea, Indigestion, Vomiting, Headache, increased bleeding tendency.

DRUGS
PRECAUTIONS:

Before taking this medication, tell your doctor if
you are allergic to dipyridamole; or to aspirin; or to other salicylates (such
as choline salicylate); or to NSAIDs (such as ibuprofen, naproxen);
or if you have any other allergies. This product may contain inactive
ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for
more details.

Before using this medication, tell your doctor or
pharmacist your medical history, especially of: aspirin-sensitive asthma (a
history of worsening breathing with runny/stuffy nose after taking aspirin or
other NSAIDs), bleeding problems (such as hemophilia, vitamin K deficiency,
low platelets), low blood pressure (hypotension), heart problems
(such as angina, heart attack), stomach problems (such as
ulcers, heartburn), kidney disease, liver disease, a
certain muscle problem (myasthenia gravis), growths in the nose (nasal polyps), bleeding
in the brain.

DRUGS
INTERACTIONS:

Drug interactions may change how your medications work
or increase your risk for serious side effects. This document does not contain
all possible drug interactions. Keep a list of all the products you use
(including prescription/non-prescription drugs and herbal products) and share
it with your doctor and pharmacist. Do not starts, stop, or change the
dosage of any medicines without your doctor’s approval.

Some products that may interact with this drug include:
corticosteroids (such as prednisone), mifepristone, ginkgo
biloba, and other drugs that can cause bleeding/bruising (including
antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen/naproxen,
“blood thinners” such as warfarin/dabigatran), riociguat.

Check all prescription and non-prescription medicine
labels carefully since many medications contain pain relievers/fever reducers (aspirin,
NSAIDs such as ibuprofen or naproxen). These drugs are similar to this medication and
may increase your risk of side effects if taken together. However, if your
doctor has directed you to take low-dose aspirin to prevent heart
attack(usually at dosages of 81-325 milligrams a day), ask your doctor if you
should continue taking the aspirin. The low dose of aspirin in this product may
not be enough to protect against heart attack. Ask your doctor or
pharmacist for more details.